If your doctor has prescribed Dermovate for a severe skin condition like eczema or psoriasis, you might have a choice between a cream and an ointment. Both contain the same powerful active ingredient, clobetasol propionate, and are equally strong.1 So, what’s the difference?
The choice is simple. It all comes down to the condition of your skin. Getting it right can make your treatment more effective and comfortable.
The Main Difference: Wet Skin vs. Dry Skin
The most important factor when choosing between the cream and the ointment is whether your skin is “wet” or “dry.”
- Dermovate Cream is best for skin that is moist or weeping.1
- Dermovate Ointment is better for skin that is dry, scaly, or has thickened.1
Dermovate Cream vs. Ointment at a Glance
This table breaks down the key differences to help you see which formulation fits your needs.
Feature | Dermovate Cream | Dermovate Ointment |
Best For | Moist, weeping, or less dry skin areas.1 | Dry, thick, or scaly skin.1 |
Texture | Lighter and less greasy. | Thicker, greasier, and more moisturizing.3 |
How it Works | Best for surfaces that are wet or oozing.4 | Provides more moisture retention for dry lesions.1 |
Key Benefit | Suitable for areas where skin rubs together. | Forms a protective barrier that locks in moisture. |
What is Dermovate?
Dermovate is the brand name for a medicine called clobetasol propionate.1 It belongs to a group of medicines called topical corticosteroids, or steroids.6
It is considered a “very potent” or “super-potent” steroid.7 This means it is very strong and is only used for severe skin conditions when weaker steroids haven’t worked.3 It works by reducing swelling, redness, and itching.1
How to Use Dermovate Safely
Whether you use the cream or the ointment, it’s important to apply it correctly.
- Apply a thin layer. Use only enough to cover the affected area.5
- Use it once or twice a day. Follow your doctor’s instructions.4
- It is for short-term use. Treatment usually lasts up to four weeks.4
- Wash your hands. Always wash your hands after applying, unless you are treating your hands.10
- Apply moisturizers first. If you also use a moisturizer, apply it and wait for it to absorb before applying Dermovate.4
Important Things to Remember
Dermovate is a powerful medicine and should be used with care.
- Avoid using it on your face. The skin on your face is thin. Only use Dermovate on your face if your doctor tells you to, and for no more than five days.12
- Keep it away from your eyes. Getting Dermovate in your eyes can lead to problems like glaucoma or cataracts.12
- Do not use it for acne. Dermovate is not for treating acne and can make it worse.10
- Do not apply to broken skin. Avoid using it on open wounds or infected areas.1
Choosing between Dermovate cream and ointment is straightforward. If your skin is moist and weepy, the cream is likely the better choice. If your skin is dry and scaly, the ointment will provide more benefit.
Always talk to your doctor or pharmacist if you are unsure. They can help you choose the best formulation to treat your skin condition safely and effectively.
Works cited
- Dermovate Cream & Ointment – Eczema – Ashcroft Pharmacy, accessed September 4, 2025, https://www.ashcroftpharmacy.co.uk/online-doctor/eczema/dermovate-cream-ointment/
- Buy Dermovate (Clobetasol) Cream or Ointment online | Pharmacy Planet, accessed September 4, 2025, https://www.pharmacyplanet.com/dermovate.html
- Buy Dermovate Online without prescription for Eczema/Psoriasis | Medical Specialists®, accessed September 4, 2025, https://www.medical-specialists.co.uk/dermovate.html
- DERMOVATE Cream and Ointment, accessed September 4, 2025, https://assets.gskstatic.com/pharma/PM-PI_portal/Ethiopia/dermovate_cream_and_ointment_et.pdf
- Buy Dermovate Cream and Ointment Online, accessed September 4, 2025, https://www.theonlineclinic.co.uk/dermovate.asp
- Dermovate Ointment: View Uses, Side Effects, Price and Substitutes | 1mg, accessed September 4, 2025, https://www.1mg.com/drugs/dermovate-ointment-327889
- Dermovate Cream vs. Other Topical Steroids: Understanding the Difference, accessed September 4, 2025, https://www.pharmacyplanet.com/blog/post/dermovate-cream-vs-other-topical-steroids-understanding-the-difference
- Dermovate Cream & Ointment – Dermovate – Eczema & Psoriasis | Pharmacy Online, accessed September 4, 2025, https://www.pharmacyonline.co.uk/online-doctor/eczema-psoriasis/dermovate/
- Clobetasol Propionate: Uses & Side Effects – Cleveland Clinic, accessed September 4, 2025, https://my.clevelandclinic.org/health/drugs/19019-clobetasol-ointment
- Buy Dermovate Cream 0.05% (Clobetasol Propionate) | Eczema and Psoriasis Treatment, accessed September 4, 2025, https://www.simplymedsonline.co.uk/eczema-psoriasis-and-dermatitis/dermovatecream.html
- Clobetasol propionate for severe inflammatory skin conditions, accessed September 4, 2025, https://patient.info/medicine/clobetasol-propionate-for-severe-inflammatory-skin-conditions-clobaderm-dermovate-etrivex
- medicines.org.uk, accessed September 4, 2025, https://www.medicines.org.uk/emc/files/pil.939.pdf
- Information for the user Dermovate 0.05% w/w Ointment clobetasol propionate Read all of this leaflet carefully – HPRA, accessed September 4, 2025, https://assets.hpra.ie/products/Human/24396/768e8b19-05b0-41fb-b1ec-42c9cd06f25f.pdf
- Dermovate Cream: Uses, Side-effects, Price, Dosage & More Info – PharmEasy, accessed September 4, 2025, https://pharmeasy.in/online-medicine-order/dermovate-cream-25gm-209155
- Can you use clobetasol on your face? – Drugs.com, accessed September 4, 2025, https://www.drugs.com/medical-answers/you-clobetasol-face-3547367/


